The article is devoted to the currently actual problem of protecting people with disabilities rights (hereinafter PWDs). This problem has been little studied and requires further research. This article considers the role of the prosecution authorities of the Kyrgyz Republic in ensuring the rights of people with disabilities, the participation of the prosecutor of the Kyrgyz Republic in court with a statement in defense of the rights, freedoms and legally protected interests of PWDs. Moreover, the article discusses the concept of "disability". The author focuses the main attention on the review of the legislation of the Kyrgyz Republic on PWDs. Moreover, the article contains the UN Declaration of the Rights of PWDs in Resolution of the thirteenth session of the UN General Assembly 3447 (XXX), which establishes the basic principles of judicial protection for PWDs. Based on the analysis of legal acts in the field of the rights of PWDs, the authors come to the conclusion that it is very important to develop methodological guidelines for prosecutors' offices taking into account international practice and requirements of international legislation, as well as national legislation of Kyrgyzstan.